KPV ALPHA - Research Grade

KPV (Anti-Inflammatory Peptide)

Informative Description:  KPV is a linear synthetic tripeptide composed of the amino acid sequence Lysine-Proline-Valina (Lys-Pro-Val). It structurally corresponds to the C-terminal fragment of alpha-melanocyte-stimulating hormone (\alpha-MSH). Despite its ultra-small molecular footprint, it is highly prominent in biological research for its potent ability to modulate inflammatory and microbial pathways without activating the melanocortin receptors associated with skin pigmentation.
Molecular Function:
 NF-\kappaB Pathway Inhibition: Operates directly inside the cellular matrix to block the translocation of nuclear factor NF-\kappaB, the master switch that triggers the transcription of pro-inflammatory cytokines.
 Cytokine Neutralization: Selectively downregulates the synthesis and secretion of key inflammatory signaling molecules, such as TNF-\alpha, IL-1$\beta$, IL-6, and IL-8, effectively mitigating the tissue inflammatory cascade.
 Direct Antimicrobial Activity: Disrupts the cellular membrane integrity of specific pathogens, actively interfering with the virulence mechanisms of microorganisms such as Candida albicans.
Primary Uses (Research Applications):
 Intestinal Inflammation & Gut Health Studies: Extensively researched in laboratory models to evaluate the repair of the colonic mucosal barrier and the management of conditions like Inflammatory Bowel Disease (IBD) and leaky gut syndrome.
 Dermatology & Cutaneous Repair Research: Utilized in scientific protocols focused on accelerating wound healing, reducing erythema (redness), and mitigating inflammatory skin conditions such as psoriasis, eczema, and dermatitis.
 Systemic Immune Modulation Models: Evaluated in biological studies for its potential to control hyperactive immune responses and scar tissue formation, offering high metabolic stability and minimal toxicity due to its compact molecular size.

IMPORTANT NOTICE
FOR RESEARCH USE ONLY.
NOT FOR HUMAN OR VETERINARY CONSUMPTION.

This product is not intended to diagnose, treat, cure, or prevent any disease.