{"product_id":"igf-1-lr3-research-grade","title":"IGF-1 LR3 - Research Grade","description":"\u003cp style=\"text-align: center;\"\u003e\u003cstrong\u003eIGF-1 LR3 (Long R3 Insulin-like Growth Factor-1)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003eInformative Description:  \u003c\/strong\u003eIGF-1 LR3 is a highly potent synthetic analog of human Insulin-like Growth Factor-1 (IGF-1). It has been structurally modified by substituting glutamic acid with arginine at position 3 (R3) and adding a 13-amino-acid peptide extension at its N-terminus (Long). This chemical alteration drastically reduces its affinity for IGF-binding proteins (IGFBPs), which significantly increases its plasma half-life to approximately 20–30 hours, compared to the brief 20-minute half-life of the standard native version.\u003cbr\u003e\u003cstrong\u003eMolecular Function:\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e Prolonged IGF-1 Receptor Activation: \u003c\/strong\u003eBy evading binding proteins, a massive amount of the peptide remains free and biologically active to bind to cellular receptors, maximizing downstream intracellular signaling.\u003cbr\u003e \u003cstrong\u003eAkt\/mTOR Pathway Stimulation:\u003c\/strong\u003e Potently triggers the Akt\/mTOR signaling cascade, the primary cellular mechanism responsible for driving protein synthesis, nitrogen retention, and overall cellular growth.\u003cbr\u003e\u003cstrong\u003e Induction of Cellular Hyperplasia: \u003c\/strong\u003eUnlike other compounds that only increase the size of existing cells (hypertrophy), IGF-1 LR3 promotes the proliferation and differentiation of satellite cells, leading to the formation of entirely new muscle fibers.\u003cbr\u003e\u003cstrong\u003ePrimary Uses (Research Applications):\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003e Extreme Muscle Growth \u0026amp; Regeneration Studies:\u003c\/strong\u003e Extensively researched in laboratory settings to analyze the development of lean muscle tissue and evaluate accelerated recovery from severe muscle tears or dystrophies.\u003cbr\u003e\u003cstrong\u003e Insulin Sensitivity \u0026amp; Nutrient Transport Research: \u003c\/strong\u003eUtilized in metabolic models to study the optimized shuttling of glucose and amino acids directly into muscle cells, effectively diverting nutrients away from adipose storage.\u003cbr\u003e \u003cstrong\u003eBone Density \u0026amp; Cartilage Regeneration Models: \u003c\/strong\u003eEvaluated in scientific protocols for its ability to stimulate the proliferation of chondrocytes and osteoblasts, which are essential for the structural repair of joints and osseous tissue.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eIMPORTANT NOTICE\u003c\/strong\u003e\u003cbr\u003eFOR RESEARCH USE ONLY.\u003cbr\u003eNOT FOR HUMAN OR VETERINARY CONSUMPTION.\u003c\/p\u003e\n\u003cp\u003eThis product is not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e","brand":"LSBonum","offers":[{"title":"10 vials  x 0.1 mg (1 mg total)","offer_id":53107445891285,"sku":null,"price":35.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0782\/7154\/5557\/files\/IGF0.1MG.jpg?v=1780254527","url":"https:\/\/lsbonumofficial.com\/products\/igf-1-lr3-research-grade","provider":"LS Bonum","version":"1.0","type":"link"}