PT-141 - Research Grade

PT-141 (Bremelanotide)

Informative Description:  PT-141 is a cyclized synthetic peptide consisting of 7 amino acids. It is a structural analog of alpha-melanocyte-stimulating hormone (\alpha-MSH) and an active metabolite of the peptide Melanotan II. Unlike other compounds that target the peripheral vascular system, PT-141 stands out in scientific research for its ability to operate directly within the central nervous system.
Peptide Function:
 Melanocortin Agonism: Functions as a non-selective agonist of melanocortin receptors, primarily binding to the MC3R and MC4R pathways in the central nervous system.
 Dopaminergic Pathway Modulation: Activates neurons within the hypothalamus, triggering the release of dopamine a key neurotransmitter responsible for regulating behavioral motivation, desire, and central biological responses.
 Vascular-Independent Mechanism: By operating via central neurochemical pathways, it elicits physiological responses without relying on the direct modulation of endothelial nitric oxide or peripheral blood pressure.
Primary Uses (Research Applications):
 Sexual Dysfunction & Libido Studies: Heavily researched in scientific models for its unique capability to address erectile dysfunction in men and hypoactive sexual desire disorder (HSDD) in women, effectively working where traditional peripheral vascular treatments fail.
 Behavioral & Motivation Research: Utilized in neuroscience protocols to analyze brain mechanisms involved in reward, motivation, and central receptor activation.
 Inflammation & Ischemia Models: Evaluated in emerging experimental studies for its cytoprotective properties and its potential to modulate the systemic inflammatory response via the melanocortin system.

IMPORTANT NOTICE
FOR RESEARCH USE ONLY.
NOT FOR HUMAN OR VETERINARY CONSUMPTION.

This product is not intended to diagnose, treat, cure, or prevent any disease.